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Conversely, metabolomic biomarkers that improve risk calibration and provide clinical net benefit beyond conventional factors can directly inform personalized care decisions (83)
Minimizing immunogenicity of biopharmaceuticals by controlling critical quality attributes of proteins
In experimental models for the induction of tissue damage, 20 mg/kg MTX was a commonly used dose for rats (Reference Moodi, Hosseini and Abedini16Reference Azadnasab, Kalantar and Khorsandi20)
Use can compound injuries and result in dependency
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