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Additionally, chronic liraglutide treatment protected synaptic plasticity impairments and, in contrast to fluoxetine, attenuated the inhibition of long-term potentiation in the hippocampus, which was induced by corticosterone in 30-day treatment [49]

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Adults receiving tirzepatide lost a mean 4.7 kg of body weight from 36 to 88 weeks compared with an 11.1 kg weight gain for the placebo group