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For current market leaders, sustained dominance will hinge on an ability to navigate an increasingly uncertain regulatory and pricing environment and manage quality and safety concerns amid heightened scrutiny of GLP-1 drugs long-term effects and off-label use
Patil and Mitra (2026) frame tongue pigmentation specifically as a "useful bedside marker" for Addison's disease, emphasizing that something visible during a simple oral examination can unlock a complex endocrine diagnosis
Huberman, Ph.D
However, in MS patients, GSH homeostasis is altered, which may contribute to the development and progression of the disease
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