In fact, there are nice guidelines out there suggesting that somebody is going to have trouble with a given medication if you take their baseline weight and if they gain 5% above that in the first month, or 7.5% in three months, or 10% in six months
Start by identifying candidates: patients with uncontrolled A1C despite metformin, those with high BMI, or individuals at cardiovascular risk
Shrestha P, Katila N, Lee S, Seo JH, Jeong JH, Yook S (2022) Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies
Fibroblast Growth Factor-21 Exerts Direct Anti-Inflammatory Effects FGF21 suppresses inflammation in NASH models, as well as in models of other inflammatory diseases