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By targeting the core region, it identifies subtypes 1a, 1b and genotype 6

4 Adverse events in PIONEER 3 1,4 Comparator AE rates are not an adequate basis for comparison of safety between products 1 Because clinical trials are conducted under widely varying conditions, AE rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice 1 AE=adverse event

Further research, including prospective studies and registry data, is needed to better understand the safety profile, potential benefits, and risks of GLP-1 therapy in individuals with Crohn's disease

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