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From a contemporary clinical perspective, these findings also align with the recently proposed cardiovascularkidneymetabolic (CKM) syndrome framework, which emphasizes the interconnected pathophysiology of metabolic dysfunction, CV disease, and kidney disease across a continuum of risk

The scientific literature confirms this pattern

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Mishra S, Srivastava S, Tripathi RD, Govindarajan R, Kuriakose SV, Prasad MNV (2006) Phytochelatin synthesis and response of antioxidants during cadmium stress in Bacopa monnieri L