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Reward Pathways: GLP-1 RAs modulate the mesolimbic reward system (including the ventral tegmental area and nucleus accumbens), potentially reducing the hedonic drive to consume palatable foods and even moderating addictive behaviors (Zheng et al., 2024)
The accumulation of the -synuclein also triggers the microglia's activation with the subsequent expression of NLRP3 inflammasome in the SN (Haque et al
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The effective concentration sits at levels so small they challenge conventional thinking about dose-response relationships in skincare
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