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Don't Want Daily Injections Some patients simply don't want to inject themselves daily for weeks
Most researchers report initial improvements within 7 to 14 days, with significant results at the 2 to 4 week mark
Treatment starts when numbing fluid is gently infiltrated under the skin in the treatment area
Among the 25 studies included in the qualitative synthesis (16 in the meta-analysis), 15 focused specifically on serum cobalamin changes (reported by baseline and post-treatment means and standard deviations in pg/mL) and 10 reported homocysteine outcomes (means and standard deviations in mmol/L)
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