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pH sensitivity matters more
In particular, due to its amphiphilic characteristics, melatonin can diffuse and easily cross all morpho-physiological barriers, such as the placenta or the bloodbrain barrier 8,9 , and it can enter all cells of the body, influencing the function of a variety of tissues 10
Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval
any use must be individualised and supervised by a qualified physician
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