Plateaus can be reached way before significant weight loss is achieved, especially with severely or morbidly obese patients who use these medications as first line treatment
Finally, the effects of liraglutide, semaglutide, and tirzepatide on blood pressure could not be reliably evaluated, as patients with pre-existing hypertension and those receiving antihypertensive treatment were included, potentially confounding blood pressure measurements
Studies indicate that with the recommended dose of 2.4 mg once a week, many individuals see substantial weight loss within 16-20 weeks
If cost, side effects, supply issues, limited results, or the thought of lifelong medication has you frustrated, weight loss surgery may offer a more durable path forward