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Inflammatory Acne or Rashes Although uncommon, a deficiency in B12 may lead to: Persistent acne-like eruptions Seborrheic dermatitis-like rashes (scaly, red patches, especially around the nose or scalp) Increased skin sensitivity and redness Some people experience inflammatory breakouts due to an imbalance in the skins bacterial profile, worsened by low B12 levels

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Side effects are minimal and typically limited to temporary redness, mild stinging, or irritation at the subcutaneous injection site, which subsides quickly