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Primer sequences are provided in Data sheet 1 : Supplementary Table S1 (synthesized by Sangon Biotech Co., Ltd., Shanghai)
Once detected, tumors were measured weekly using calipers until they had reached a volume of 2.5 cm 3 in size for a single mass or a total volume of 5 cm 3 for multifocal tumors, at which point mice were euthanized in accordance with approved facility protocols
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