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Phentermine triggers norepinephrine release in the brain, creating a mild fight-or-flight response that suppresses hunger

These associations remained consistent across subgroup analyses, including patients using tirzepatide as adjunctive therapy to other first-line diabetes agents, among patients older than 60 and comparisons against individual GLP-1 drugs, including semaglutide and dulaglutide

Continuous monitoring, automated phenotyping, digital biomarkers, and FAIR data standards transform what we can measure