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Vitamin B12 deficiency has been linked to fatigue, tingling or loss of feeling in the extremities, irritability, memory impairment, depression, anemia, irritable bowel syndrome (IBS), constipation, poor wound healing, dry or damaged looking skin, and neurological disorders

They are particularly beneficial for older adults and those with conditions that impair B12 absorption

You're managing two half-lives, two sets of side effects, two storage requirements, and potential interactions that no tox screen has evaluated