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As a result, many healthcare providers now prescribe these drugs as part of a comprehensive treatment plan for obesity, particularly for patients with comorbidities such as type 2 diabetes, heart disease, and hypertension

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Discussion Metabolic profiling and the absence of putative genes encoding important enzymes of the Embden-Meyerhof-Parnas and Entner-Doudoroff pathway suggest that, in contrast to the closely related H