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doi: 10.1210/jc.2004-1719 98 MericqVCassorlaFBowersCYAvilaAGonenBMerriamGR

DOI: 10.3389/fendo.2012.00131

The Increlex label cites preclinical 2-year rat carcinogenicity studies in which increased mammary and skin tumor incidence occurred at high IGF-1 exposure

On one hand, FGF21 appears to increase peripheral anabolic signaling, for example through muscle and adipose tissue insulin sensitization, under conditions of adequate or excessive energy intake, as described in detail below

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