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All assays were performed following the manufacturers recommendations
Given the conserved role of this pathway on lifespan, therapeutic strategies, such as insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibodies (mAb), represent a promising translational tool to target human aging
Ferraro, E., German, M., Mollace, R., Mollace, V
Statistical analysis All datasets represent the means SD of at least three biological replicates
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