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Function [edit] Neurotransmitter [edit] Two general classes of GABA receptor are known: [6] GABA A in which the receptor is part of a ligand-gated ion channel complex [7] GABA B metabotropic receptors, which are G protein-coupled receptors that open or close ion channels via intermediaries (G proteins) Neurons that produce GABA as their output are called GABAergic neurons