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use cautiously in patients with gout [16] [25] Myopathy risk : When combined with statins, increased risk of muscle symptoms requires monitoring Glucose effects : Dose-dependent increases in blood glucose and A1c Monitoring recommendations: Glucose monitoring is paramount, particularly during the first few weeks after initiating or adjusting either medication

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Patients can expect to see noticeable weight loss within the first few weeks of treatment, with continued progress over the following months