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2 h An 8-week dose-escalation regimen was used, with dose escalation from 0.25 mg per week for 4 weeks then 0.5 mg per week for another 4 weeks, followed by maintenance dose of 1 mg per week throughout remainder of the treatment period

When the cellular GSH levels were artificially lowered or raised, TRaQ-G probes reliably detected changes in GSH concentration

Additional reductions are observed in inflammatory mediators including monocyte chemoattractant protein-1 (MCP-1), inducible nitric oxide (NO) synthase (iNOS), and NO production [66, 109, 110]

This type of exercise helps to build and preserve lean muscle mass, offsetting the 2530% lean mass loss that can occur in studies of rapid weight reduction