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PMC8618295
In these cases, the weight-related health risk is immediate and serious, the drugs cardiovascular and metabolic benefits are well-evidenced, and the risk-benefit calculation clearly favours pharmacological intervention
But we were also curious about how GLP-1 and GIP impacted insulin and glucagon secretion. Researchers were surprised to find there were no differences with glycemic control even though the kidney disease patients were secreting more GLP-1 and GIP
This widespread distribution means GLP-1 affects multiple systems simultaneously
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