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Some patients reach a weight loss plateau on tirzepatide despite dose optimization, suggesting their body has adapted to dual GLP-1/GIP stimulation

Before starting tirzepatide, our providers will review your medical history, health, and goals

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As retatrutide remains an investigational medicine without full regulatory approval in the UK, it is important that any suspected side effects are reported via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or via the Yellow Card app, in addition to informing your trial team