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For older adults or those with coronary artery disease, lower starting doses with gradual titration are recommended
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It is evident from these studies that the mechanism of action of GLP-1Ras remains unclear and its effect on tumors is still controversial
GLP-1RA-induced microbial shifts also attenuate chronic low-grade systemic inflammation by reducing pro-inflammatory cytokines, including tumor necrosis factor- (TNF-) and interleukin-6 (IL-6), which supports muscle protein integrity and recovery [154,155]
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