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Activation of TLRs is a cornerstone of innate immunity, triggering key defense responses against invading pathogens (260)
10.1111/j.1463-1326.2009.01109.x 155 HermansenK.SchmitzO.ArnfredJ.MogensenC
These include recipients of stem cell or solid-organ transplants receiving anti-rejection therapy
This disorder is inherited in an autosomal recessive pattern, which means the defective gene is located on an autosome, and two copies of the gene - one from each parent - are required to be born with the disorder
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