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Intramuscular administration bypasses oral absorption, which is limited to approximately 12% of dose above 1,000 mcg due to intrinsic factor saturation in the ileum

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What may improve includes: Pain intensity and frequency Radiating symptoms (sciatica) Morning stiffness and mobility Tolerance for sitting, standing, and daily activities Sleep quality affected by pain Dependence on pain medications Many users with disc herniations report 50% to 80% improvement in symptoms while their imaging findings remain unchanged

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