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If you constantly feel like youre on edge or battling mood swings, your genetics may play a role

This post-translational modification is now recognised as a major mechanism of redox-regulated cell signalling, controlling the activity of transcription factors, kinases, phosphatases, and metabolic enzymes in response to the intracellular redox environment

52 An implication of this model is that ferroptotic contagion may, under certain conditions, behave analogously to other excitable biological wave systems, such as calcium waves or spreading depolarization, in which local activation is continuously regenerated rather than physically transmitted over long distances

MZB differentiation is blocked in Gclc -deficient mice The loss of MZB in Gclc fl/fl Mb1-Cre + mice prompted us to investigate the possibility of defects in the trafficking of MZB in the spleen