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The downstream effects include activation of hormone-sensitive lipase in adipose tissue (which breaks down stored triglycerides into free fatty acids), increased protein synthesis in skeletal muscle, enhanced cellular repair and turnover, elevated IGF-1 production from the liver, and improved lipid metabolism including reduced triglycerides
Another alarming trend is the undisclosed addition of certain pharmaceutical agents into allegedly natural supplements
In recombinant cell systems it produces full agonist responses at GLP-1R and GCGR with sub-nanomolar potency and partial agonism at GIPR
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