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Overall, the primary composite endpoint occurred in 331 patients of 1767 (18.7%) on Ozempic (1 mg) and 410 patients of 1766 (23.2%) on placebo (HR, 0.76 [95% CI: 0.66-0.88] P =0.0001 for superiority)
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Safety Profile in Research Contexts Gastrointestinal events (nausea, vomiting, diarrhea, constipation) remain the most common adverse effects, typically mild to moderate, dose-dependent, and often mitigated by gradual dose escalation starting at lower levels (e.g., 2 mg)
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