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Thus, current efforts are focused on preserving basal autophagy levels in podocytes, a goal achievable through the administration of antioxidant compounds such as berberine, mangiferin, notoginsenoside R1, and geniposide ( Excessive OS exerts a dual impact on the integrity of the glomerular filtration barrier, both inducing dysfunction and exacerbating proteinuria and renal decline

Losartan belongs to the class of medicines called angiotensin II receptor antagonists