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The SURPASS-CVOT trial (NCT04255433) will assess the cardiovascular safety of tirzepatide compared to dulaglutide in people with T2D and established atherosclerotic disease [111]
Because they bypass thyroid function to address hunger and satiety, GLP-1 compounds can be effective for weight loss even when thyroid levels are properly managed with medication
Y., Pollak, M., Azoulay, L
Clinical trials lasting 68 weeks and longer show that people who continue treatment are more likely to achieve and sustain meaningful weight loss compared to those who stop therapy
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