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Abbreviations CAT: Catalase CF: Cisplatin plus 5-fluorouracil DEGs: Differentially expressed genes EC: Esophageal cancer EMT: Epithelialmesenchymal transition ESCC: Esophageal squamous cell carcinoma FC: Fold change FDR: False Discovery Rate FFPE: Formalin-fixed paraffin-embedded GO: Gene Ontology GPx: Glutathione peroxidase GSEA: Gene set enrichment analysis GSH: Glutathione GST: Glutathione S-transferase H&E: Hematoxylin and eosin ICI: Immune checkpoint inhibitors INDELs: Insertions/deletions KEGG: Kyoto Encyclopedia of Genes and Genomes NAC: Neoadjuvant chemotherapy OS: Overall survival PC1: First principal component PCA: Principal Component Analysis PostNAC: After CF-based NAC PPI: Proteinprotein interaction PreNAC: Before CF-based NAC ROS: Reactive oxygen species SNVs: Single-nucleotide variants SOD: Superoxide dismutase TPM: Transcripts per million References Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al

This aligns well with the first dose experience that many GLP-1 users describe, where that initial adjustment period benefits from scheduling flexibility

These effects help your body maintain a lower weight

That combination tends to help people who struggle with insulin resistance or hormonal patterns that make ordinary dieting frustrating