Although usually only observed when GLP-1 RA is used in combination with insulin or SU, risk of hypoglycaemia is another reported AE in people treated with GLP-1 RAs [16, 18, 20, 22, 24, 26, 28]
Alternatives include intensive lifestyle modification programs, other weight management medications like phentermine-topiramate or naltrexone-bupropion, different diabetes medications such as SGLT-2 inhibitors, and bariatric surgery for severe obesity
SGLT2 inhibitors in patients with heart failure: A comprehensive meta-analysis of five randomised controlled trials
The primary measures used to evaluate the drugs effects were changes in the patients scores on the Unified Parkinson Disease Rating Scale (UPDRS), which measures their ability to perform daily activities and motor function