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Renal Function: Since the breakdown products of semaglutide are excreted through the kidneys, impaired renal function can affect the elimination rate of these products, potentially leading to altered drug levels and effects

For constipationwhich can also occur with Ozempic due to delayed gastric emptyingspecific Bifidobacterium lactis strains (such as HN019 and BB-12) have shown promise in improving stool frequency and consistency in clinical trials of functional constipation

Rather than relying on myths or headlines, patients are best served by understanding that this medicine is part of a broader medical approach to obesity care, which may also include nutrition, physical activity, sleep support, behavior change, and, for some people, obesity surgery