glp 1 agonist and dpp 4 inhibitor How does sitagliptin work? DPP-4 inhibitors GLP-1 mimetics The Role of DPP-4 Inhibitors

Promotes hyperplasia (creation of new muscle fibers) Accelerates muscle repair and recovery post-exercise Enhances nutrient transport and cellular growth signaling IGF1 induces proliferation and differentiation of muscle satellite cells, enabling hypertrophic adaptations in response to overload. Adams et al., Journal of Applied Physiology Muscle Preservation Post-Cycle IGF1 LR3 helps preserve lean mass during post-cycle therapy (PCT) or caloric restriction

A clinical study involving 564 adults (BMI 30-40 kg/m2, without T2DM) found that compared with orlistat (3120 mg, weight loss of 4.1 kg), LIR (subcutaneous administration of 1.2 mg/d, 1.8 mg/d, 2.4 mg/d or 3 mg/d) had an average weight loss of 4.8-7.2 kg, the two-year extended experiment of which also showed similar results (88, 89)

[PMID: 25415472] PubMed record related to this compound for laboratory literature review

Ghadernezhad N, Khalaj L, Pazoki-Toroudi H, et al