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Structural optimization: Further reduce IGFBP binding ability through site directed mutagenesis, or introduce transmembrane peptides to enhance tissue penetration
Regulated PTMs including phosphorylation, acetylation, ubiquitination, and glycosylation participate in elaborate cellular signaling networks
You can think of glutathione as your skin's beauty editor
Studies with complete reporting and rigorous design were rated as "High," while others with some limitations or missing methodological details were rated as "Medium" or "Low." To evaluate the reliability and scientific rigor of the evidence presented in this review, we conducted a methodological quality assessment of the primary clinical trials included
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