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Acetaminophen (APAP) toxicity generally becomes apparent within the initial 24-h period following administration
Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs
Yang L, Tian S, Chen Y, Miao C, Zhao Y, Wang R, et al
ACCORD Study Group
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