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Given that cystine starvation activated the GCN2-eIF2-ATF4 axis, we evaluated the expression of several AARE-containing genes

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Research indicates retinol may also support mitochondrial function and counteract photo-oxidative stress in dermal fibroblasts through multiple signaling pathways including those related to cellular senescence

Endothelial cells associated with tumors secrete growth factors such as vascular endothelial growth factor (VEGF), Notch ligands, and nitric oxide, which enables the cancer cells proliferation and self-renewal (127)