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Three main paths exist: Weeks 37-48 Summary: Completion and Planning Weight loss: 3-7 pounds this period (49-53 pounds total, ~24% of starting weight average) Weekly loss rate: 0.25-0.6 pounds weekly (minimal but still progressing) Final results: 24.2% average total body weight loss by week 48 Discontinuation rate: 1-2% during this period Overall completion rate: 74% of people who started week 1 completed week 48 Psychological state: Proud of achievement, planning next steps What Actually Determines Your Timeline Results Individual timelines vary from the averages presented
The American Journal of Gastroenterology, 113 (1), 115123
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The September 2024 LIFT-AD trial termination after meeting enrollment demonstrates that this approach, despite decades of development, does not slow Alzheimer's cognitive decline in humans
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