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The FDA maintains a drug shortage database based on several key criteria: When manufacturers report anticipated disruptions or discontinuances in drug production When the FDA becomes aware of significant supply issues through market surveillance When healthcare providers or patients report consistent difficulty obtaining medications When a drug's demand significantly exceeds available supply On October 30, 2024, Novo Nordisk confirmed that all doses of Wegovy and Ozempic are now listed as available in the U.S., although the company cautioned people may still experience variability in filling their prescriptions

Holmes et al, 1998

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Every square inch of skin contains approximately 20 blood vessels, 60,000 melanocytes (which provide pigmentation and guard against UV radiation), 650 sweat glands, and thousands of nerve endings