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Results: The 18-month risk for ION was 8.5 versus 5.5 per 10 000 among GLP-1RA users versus SGLT2i users (RD, 3.0 [95% CI, 0.4 to 5.7]) and 7.8 versus 4.2 per 10 000 among GLP-1RA users versus DPP4i users (RD, 3.6 [CI, 1.1 to 6.1])

Study 2 This study re-randomized 177 HIV-infected patients with lipodystrophy who completed tesamorelin treatment in the Main Phase to receive either tesamorelin (N=92) or placebo (N=85) for an additional 26-week duration (1:1 randomization ratio)