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Clinical Implications The growing prevalence of GLP-1 receptor agonist and dual incretin agonist use necessitates increased awareness among anesthesiologists, surgeons, gastroenterologists, endocrinologists, primary care clinicians, and perioperative nursing teams
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The Small Molecule Penalty: Evidence of R&D Shift The IRAs 9-year versus 13-year differential, which some have called the small molecule penalty, has generated documented changes in R&D investment allocation within approximately 24 months of the laws passage
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