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Drug Release and Protection: The release of a large amount of SNAC leads to a local rise in pH, which reduces the activity of pepsin
It focuses on using better materials, machine learning for data analysis, and chemometric techniques
It was first reported by Sawyer, Hruby, Hadley and colleagues in the Proceedings of the National Academy of Sciences in 1980, and it departs from native human alpha-MSH at only two of thirteen positions: norleucine replaces the oxidation-prone methionine at position 4, and the phenylalanine at position 7 is inverted to its D-enantiomer
Its derived from a protein naturally found in the stomach, where it plays a protective and healing role
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