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Other recognised contributors to RLS include chronic kidney disease (particularly uraemia), pregnancy, and certain medications such as some antidepressants (SSRIs/SNRIs), antipsychotics, and dopamine antagonists (including anti-nausea medications like metoclopramide)

MHT works by replacing the estrogen that declines during perimenopause and menopause

Considering dopamines pivotal role in the brains reward system, such alterations could lead to an imbalance in dopaminergic neurotransmission 43,44

But ALA supplements are widely available, and alpha-lipoic acid is included in some multivitamin and antiaging formulas