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In fact, DPP-4 inhibitors, aimed at elongating effect of endogenous incretins, are available for the treatment of type 2 diabetes though the glycemic effect of these medications are comparatively modest [24]

Educate patients that: Gastrointestinal side effects are common early on Symptoms are typically temporary and improve over time Side effects are often more noticeable during dose escalation Providers can adjust dosing if symptoms become difficult to manage 2

Our study establishes that RSL3 contributes both to thyroid tumor cell DNA damage and concomitant inhibition of DNA damage repair response by limiting the availability of pNPM1 (T199)

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