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MSM, an endogenous cellular metabolite that acts as sulphur donor in many transmethylation reactions, is also able to act as an antioxidant and free radical scavenger
Thiamine has long been studied for its role in neurological function, and thiamine derivatives have been shown on numerous occasions to improve diabetic neuropathy through reducing oxidative stress, improving redox status and nerve cell regeneration (here, here and here)
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For others, they can become chronic and severely affect quality of life
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