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Adverse Reactions Clinical Trials Experience The most commonly reported adverse reactions are hypersensitivity (e.g., rash, urticaria) reactions due to the effect of GH (e.g., arthralgia, extremity pain, peripheral edema, hyperglycemia, carpal tunnel syndrome), injection site reactions (injection site erythema, pruritis, pain, urticaria, irritation, swelling, hemorrhage)
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The potential risks of administering a degraded or contaminated preparation including injection-site reactions, systemic infection, or unpredictable pharmacological effects outweigh the cost of replacing the vial
Gratzl S, Rodriguez PJ, Cartwright BMG, Baker C, Do D, Stucky NL
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