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It has been reported that GSH is reduced by the following side reactions under neutral conditions (Methods in Enzymology, 1985, 113, 548)

Nutrient signals like glucose and fats, as well as hormonal signals including glucagon-like peptide-1 (GLP-1), glucagon-like peptide-2 (GLP-2), Peptide YY (PYY), ghrelin, cholecystokinin (CCK), and bile acids, enter the central nervous system (CNS) through the bloodstream or the vagus nerve

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