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Autosomal-dominant mode of inheritance of a melanocortin-4 receptor mutation in a patient with severe early-onset obesity is due to a dominant-negative effect caused by receptor dimerization
R., Schulte, R., Le, P., & Rothberg, M
[3] Meyre, D., Mohamed, S., Gray, J.C
These synthetic analogs are also chemically modified to resist enzymatic degradation, allowing them to remain active in your bloodstream for hours to days rather than minutes
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