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A high GSH to GSSG ratio signals a healthy redox state
Similarly, redox-responsive carriers incorporating disulfide bridges (cleaved by elevated glutathione in activated microglia or neurons) liberate bacosides or quercetin exactly at sites of neuroinflammation, amplifying Nrf2 activation and neuroprotection while remaining inert during circulation (180)
Progress in Neuropsychopharmacology & Biological Psychiatry
N-acetycysteine (NAC) is metabolized or converted by the body into glutathione
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