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Conjugated linoleic acid (CLA) is a naturally occurring fatty acid that has been extensively studied for its potential to support fat loss and improve body composition
As of September 2023 it is on the FDA's Category 2 list of bulk drug substances that may not be compounded due to significant safety risks, and the agency has scheduled a Pharmacy Compounding Advisory Committee (PCAC) review for July 2026 covering proposed uses in opioid withdrawal, chronic insomnia, and narcolepsy
There is no oral form of this blend that survives digestion, which is another reason the protocol is framed entirely around a small subcutaneous dose
Br J Pharmacol 2016;173:1820-34.ArticlePubMedPMC 48
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